Beta Sitosterol


Generic Medicine Info
Indications and Dosage
Oral
Nutritional supplementation
Adult: Usually incorporated in margarine, yogurt and foods: 1.5-3 g daily.
Special Precautions
Safety and efficacy are not established in pregnancy and lactation. Caution when used in patients with asthma or breathing disorders, DM, primary biliary cirrhosis, ileostomy, neurodegenerative disorders (like Parkinsonism or Alzheimer's disease), diverticular disease, short bowel syndrome, celiac disease and sitosterolaemia. History of gallstones.
Adverse Reactions
May cause constipation, diarrhoea, difficulty breathing and nausea.
Drug Interactions
Activated charcoal may slightly reduce serum levels of beta sitosterol. Concurrent admin with ezetimibe may reduce serum levels of beta sitosterol in patients with sitosterolaemia. May have synergistic effects when used with HMG-coenzyme A reductase inhibitors.
Food Interaction
May reduce absorption of fat-soluble vitamins e.g. carotenes and vitamin E.
Action
Description:
Mechanism of Action: Beta-sitosterol is a plant sterol that is commonly found in fruits, vegetables, soybeans, breads, peanuts and peanut products. It is also found in bourbon and oils e.g. olive and flaxseed. It is reported to lower cholesterol and aid in symptomatic improvement in mild to moderate benign prostatic hypertrophy.
Storage
Store below 25°C.
MIMS Class
Supplements & Adjuvant Therapy
Disclaimer: This information is independently developed by MIMS based on Beta Sitosterol from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2024 MIMS. All rights reserved. Powered by MIMS.com
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